Test: GRE Subject Test: Biochemistry, Cell, and Molecular Biology

1.

How do Bax and Bak promote cell death?

They allow the release of cytochrome c from the mitochondria into the cytosol, which activates procaspase

They bind and block Bcl2 from inhibiting Bax and Bak activators

They cleave procaspase into caspase, which initiates the caspase cascade

They are a major component of the apoptosome

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