Test: GRE Subject Test: Biochemistry, Cell, and Molecular Biology

1.

Which of the following descriptions reflects a nonsense mutation?

A mutation in a gene causes a valine to be replaced by a glutamic acid residue in the final protein product.

A uracil is replaced by an adenine in the primary transcript, resulting in a severely shortened final protein product.

An adenine is improperly added into a gene, resulting in a completely different amino acid sequence downstream to the mutation.

A transition mutation changes one nucleotide in a gene, but the final protein still has the same amino acid structure as it did prior to the mutation.

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